- The move broadens treatment choices for pediatric patients aged 10 years and older whose diabetes remains uncontrolled with existing therapies. Medscape Medical News
- Trial results showed improvements in symptoms, exercise capacity, and left ventricular outflow obstruction. Medscape Medical News
- Despite reported slowing of progression, regulators said the evidence on the novel oral agent blarcamesine did not support a positive benefit-risk balance. Medscape News Europe
- The decision applies to adolescents and adults and aligns with earlier US authorization for higher-risk groups. Medscape News Europe
- Phase 3 studies point to sustained disease control in patients who remain symptomatic despite standard therapies. Medscape Medical News
- The recommendation addresses a long-standing treatment gap for patients facing bladder removal after standard therapy fails. Medscape Medical News
- An elegant study in post-TAVI atrioventricular block, a PSA for my structural colleagues, revascularization in women, and a CTO PCI trial are the topics John Mandrola, MD, discusses in this week’s podcast. theheart.org on Medscape
- Dr Suchitra Sundaram shares key highlights on frontline time limited and all oral regimens producing deep MRD responses, alongside novel relapsed/refractory agents. Medscape
- The move broadens treatment choices for pediatric patients aged 10 years and older whose diabetes remains uncontrolled with existing therapies. Medscape Medical News
- Trial results showed improvements in symptoms, exercise capacity, and left ventricular outflow obstruction. Medscape Medical News
- Despite reported slowing of progression, regulators said the evidence on the novel oral agent blarcamesine did not support a positive benefit-risk balance. Medscape News Europe
- The decision applies to adolescents and adults and aligns with earlier US authorization for higher-risk groups. Medscape News Europe
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- A decade-long study of older women found that tea drinkers had slightly stronger bones, while moderate coffee drinking caused no harm. Heavy coffee intake—over five cups a day—was linked to lower bone density, especially in women who consumed more alcohol. Tea’s benefits may stem from catechins that support bone formation. The researchers say small daily […]
- Scientists exploring how the brain responds to stress discovered molecular changes that can influence behavior long after an experience ends. They also identified natural resilience systems that help protect certain individuals from harm. These findings are opening the door to treatments that focus on building strength, not just correcting problems. The work is also fueling […]
- A new analysis suggests that people with type 2 diabetes who use GLP-1 medications like Ozempic, Trulicity or Victoza may be less likely to develop epilepsy than those taking DPP-4 inhibitors. Semaglutide showed the strongest connection to lowered risk. Researchers caution that the findings show an association, not proof of cause and effect. More rigorous […]
- Researchers discovered that children who went back to school during COVID experienced far fewer mental health diagnoses than those who stayed remote. Anxiety, depression, and ADHD all declined as in-person learning resumed. Healthcare spending tied to these conditions also dropped. Girls showed the largest improvements, highlighting the importance of school-based structure and support.
- Researchers used AI to pinpoint a little-known monkeypox protein that provokes strong protective antibodies. When the team tested this protein as a vaccine ingredient in mice, it produced a potent immune response. The discovery could lead to simpler, more effective mpox vaccines and therapies. It may also help guide future efforts against smallpox.
- Scientists discovered that certain gene changes allow cells to function even when frataxin, the protein lost in Friedreich’s ataxia, is missing. Experiments in worms, human cells, and mice revealed that lowering a gene called FDX2 helps restore vital energy processes. The work points to a new, more targeted treatment strategy.
- Environmental Phenols and Growth in Infancy: The Infant Feeding and Early Development Studyhttps://pubmed.ncbi.nlm.nih.gov/38753668/
- Residential Proximity to Toxic Metal-emitting Industrial Sites and Toenail Metal Concentrations in a United States-wide Prospective Cohorthttps://pubmed.ncbi.nlm.nih.gov/38908662/
- Effects of Developmental Lead and Phthalate Exposures on DNA Methylation in Adult Mouse Blood, Brain, and Liver: A Focus on Genomic Imprinting by Tissue and Sexhttps://pubmed.ncbi.nlm.nih.gov/38833407/
- Coordinated DNA Polymerization by Polγ and the Region of LonP1 Regulated Proteolysishttps://pubmed.ncbi.nlm.nih.gov/38932681/
- Subchronic Inhalation Exposure to Ultrafine Particulate Matter Alters the Intestinal Microbiome in Various Mouse Modelshttps://pubmed.ncbi.nlm.nih.gov/38242419/
- Integrated Approach for Testing and Assessment for Developmental Neurotoxicity (DNT) To Prioritize Aromatic Organophosphorus Flame Retardantshttps://pubmed.ncbi.nlm.nih.gov/38922117/
- MRI with the ENZIAN and #ENZIAN scoring systems vs surgery shows high accuracy and reliability for deep endometriosis in key pelvic compartments, especially the ovary, a meta-analysis finds. Medscape News UK
- A retrospective study of all applicants for US rheumatology training from 2009 to 2024 found a persistent surplus of applicants relative to positions, highlighting the field’s competitiveness. Medscape Medical News
- Eli Lilly said on Thursday its next-generation obesity drug helped patients lose an average of 28.7% of their weight in a late-stage trial, outperforming its blockbuster… Reuters Health Information
- Chronic chikungunya arthritis often mimics rheumatoid arthritis, complicating diagnosis and therapy, and necessitating careful immunosuppression decisions. Medscape News Europe
- The remission of childhood overweight before young adulthood reverses the risk for coronary heart disease in adulthood; however, gaining weight during puberty significantly increases the future risk. Medscape News UK
- A retroperitoneal mass in a 75-year-old man mimics malignancy but proves to be an implant-related inflammatory reaction complicated by recurrent infections. Medscape UK
