- In patients with heart failure, SGLT2 inhibitors after TAVI are associated with major risk reductions in a clinical trial that multiple experts are calling practice changing. Medscape Medical News
- Co-production deals with adalimumab biosimilar manufacturers and PBMs have increased biosimilar adoption, but this consolidation of the drug supply chain could undercut competition. Medscape Medical News
- Previous skepticism turns to optimism as the first clinical trials for transplantation with genetically edited pig kidneys gain FDA approval. Medscape Medical News
- Updated phase 2 results of the KEYNOTE-799 trial were presented at ELCC 2025. Medscape Medical News
- Wide-ranging challenges include staffing, technology upgrades, community outreach. Medscape Medical News
- An exploratory analysis shows a reduction in extrathoracic metastases and prolonged time to progression or death due to any metastases with durvalumab vs placebo. Medscape Medical News
- Get the latest on the measles resurgence: how to spot it fast, counsel patients, and avoid misdiagnosis. Stay sharp with practical tools to protect your patients and your practice. Medscape
- Dr Kathleen Moore emphasizes the need for a more nuanced approach to endometrial cancer treatment, particularly in the heterogeneous mismatch repair-proficient population. Medscape
- Read clinically focused news coverage of key developments from WCM-EADO 2025 Medscape Oncology
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- Drug-carrying DNA aptamers can deliver a one-two punch to leukemia by precisely targeting the elusive cancer stem cells that seed cancer relapses, researchers report. The aptamers — short single-strand snippets of DNA that can target molecules like larger antibodies do — not only deliver cancer-fighting drugs, but also are themselves toxic to the cancer stem […]
- Early administration of the drug Fosdenopterin/rcPMP improves the chances of survival of infants with MoCD type A and promotes the development of brain functions.
- Researchers developed a manufacturing technique that rapidly generates large quantities of nanoparticles coated with drug-delivering polymers, which hold great potential for treating cancer. The particles can be targeted directly to tumors, where they release their payload while avoiding many of the side effects of traditional chemotherapy.
- Researchers found that a small population of immune cells in the mouse intestine prevents allergic responses to food, suggesting that targeting such cells therapeutically could potentially lead to a new treatment for allergies.
- In the fight against bacterial pathogens, researchers are combining vaccination with targeted colonization of the intestine by harmless microorganisms. This approach could potentially mark a turning point in the antibiotics crisis.
- A team of researchers has uncovered a key cellular mechanism that affects the function of mRNA vaccines and therapeutics. Their study provides the first comprehensive understanding of how mRNA vaccines are delivered, processed, and degraded within cells — a breakthrough that could pave the way for more effective vaccines and RNA-based treatments.
- https://pubmed.ncbi.nlm.nih.gov/38908662/
- https://pubmed.ncbi.nlm.nih.gov/38753668/
- https://pubmed.ncbi.nlm.nih.gov/38932681/
- https://pubmed.ncbi.nlm.nih.gov/38833407/
- https://pubmed.ncbi.nlm.nih.gov/38922117/
- https://pubmed.ncbi.nlm.nih.gov/38242419/
- Dr JR Smith discusses the formula for success in medical school. Medscape
- Tracy Beth Hoeg, a sports medicine physician and epidemiologist who opposed key U.S. health policies during the COVID-19 pandemic and questioned the use of some childhood… Reuters Health Information
- The effect of glucagon-like peptide 1 receptor agonists on patients with joint infections was a popular topic at the American Academy of Orthopaedic Surgeons 2025 annual meeting. Medscape Medical News
- Ethicist Art Caplan discusses progress in gene therapy research and the need for medical professionals and regulators to tolerate appropriate risk. Medscape Business of Medicine
- The first prospective study to look at this problem since investigators identified an issue earlier confirmed that clinicians should ‘pause’ when making decisions on the measurements. Medscape Medical News
- HLA-B27 positivity is linked to higher odds of non-remission in patients with juvenile idiopathic arthritis at 18 years after disease onset, with the odds being higher in men than in women. Medscape News UK