- A sharp increase in IMGs leaving the UK has prompted warnings that harsher rhetoric and stalled opportunities may drive talent elsewhere. Medscape News UK
- Medscape Medical News spoke recently with the new AAFP president about the challenges facing family medicine specialists and her goals for her term leading the group. Medscape Medical News
- NICE has recommended vutrisiran for routine NHS use in adults with transthyretin amyloidosis with cardiomyopathy, offering a new disease-modifying option alongside tafamidis. Medscape News UK
- More training and fellowships are leading nurse practitioners toward dermatology, where demand remands. Medscape Medical News
- Office-based models are becoming more economically viable, along with the benefits of greater autonomy and time optimization, GI experts write. Medscape Medical News
- Working ‘off hours’ can throw of circadian rhythms, making diet and sleep routines important. Medscape Medical News
- Dr Amal Mattu discusses recent studies showing that cannabis use can increase a person’s risk for cardiovascular events like myocardial infarction, ischemic stroke, and heart failure. Medscape Emergency Medicine
- Dr Wilkoff wonders whether a diagnosis can be both therapeutic and a self-fulfilling prophecy. Medscape Pediatrics
- The management of obesity remains foundational to the treatment of obstructive sleep apnea, and the future of OSA care lies in an integrated metabolic-sleep model of care. Medscape Europe
- Listener feedback, huge news in the world of carotid disease with the CREST-2 publication, prasugrel beats ticagrelor again, and a big coffee trial are the topics John Mandrola, MD, discusses in this week's podcast. theheart.org on Medscape
- A sharp increase in IMGs leaving the UK has prompted warnings that harsher rhetoric and stalled opportunities may drive talent elsewhere. Medscape News UK
- A gel-encapsulated polypill with three of the four pillars for patients with heart failure increased adherence. Dr Ambarish Pandey, investigator on the POLY-HF trial, speaks to Dr Ileana Piña about the findings. theheart.org on Medscape
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- A new nasal-delivered nanotherapy shows promise against aggressive glioblastoma tumors. By activating the STING immune pathway using gold-core spherical nucleic acids, researchers were able to reach the brain without invasive surgery. When paired with drugs that boost T-cell activity, the treatment eliminated tumors in mice and built long-lasting immunity. The results suggest a powerful new […]
- A first-of-its-kind trial is testing adult stem cell transplants for advanced dry macular degeneration. Early results show the treatment is safe and can significantly improve vision, even in severely affected patients. Participants gained measurable sight improvements in the treated eye. Researchers are now monitoring higher-dose groups as the therapy advances toward later trial phases.
- People who smoke only a couple of cigarettes a day still face surprisingly high risks of heart problems and early death. A large review of long-term studies shows that even very light smokers can see their risk of heart failure climb sharply. While quitting leads to major health improvements, some risk remains for decades. The […]
- Researchers uncovered how estrogen subtly reshapes learning by strengthening dopamine reward signals in the brain. Rats learned faster when estrogen levels were high and struggled when the hormone’s activity was blocked. The findings help explain how hormonal cycles influence cognitive performance and psychiatric symptoms. This connection offers a new path for understanding brain disorders tied […]
- A massive real-world study comparing tirzepatide and semaglutide reveals both drugs deliver strong, early cardiovascular protection—reducing heart attack, stroke, and death in adults with type 2 diabetes. While companies have claimed large differences favoring their own medications, researchers found only modest distinctions between the two blockbuster GLP-1 drugs.
- Researchers discovered that the common amino acid arginine can block harmful Aβ aggregation and reduce its toxic effects in Alzheimer’s disease models. In flies and mice, oral arginine lowered plaque levels, reduced inflammation, and improved behavior. Its strong safety record and low cost make it a promising repurposing candidate. The findings hint at a surprisingly […]
- Environmental Phenols and Growth in Infancy: The Infant Feeding and Early Development Studyhttps://pubmed.ncbi.nlm.nih.gov/38753668/
- Residential Proximity to Toxic Metal-emitting Industrial Sites and Toenail Metal Concentrations in a United States-wide Prospective Cohorthttps://pubmed.ncbi.nlm.nih.gov/38908662/
- Effects of Developmental Lead and Phthalate Exposures on DNA Methylation in Adult Mouse Blood, Brain, and Liver: A Focus on Genomic Imprinting by Tissue and Sexhttps://pubmed.ncbi.nlm.nih.gov/38833407/
- Coordinated DNA Polymerization by Polγ and the Region of LonP1 Regulated Proteolysishttps://pubmed.ncbi.nlm.nih.gov/38932681/
- Subchronic Inhalation Exposure to Ultrafine Particulate Matter Alters the Intestinal Microbiome in Various Mouse Modelshttps://pubmed.ncbi.nlm.nih.gov/38242419/
- Integrated Approach for Testing and Assessment for Developmental Neurotoxicity (DNT) To Prioritize Aromatic Organophosphorus Flame Retardantshttps://pubmed.ncbi.nlm.nih.gov/38922117/
- FDA proposals include ‘major updates’ to simplify biosimilarity studies, reduce unnecessary clinical testing, and ease the process for making biosimilars interchangeable with brand-name biologics. Medscape Medical News
- Identifying the symptoms can help you steer patients to solutions, including a wrist brace, steroid injections and, in serious cases, surgery. Medscape Medical News
- Within 1 year of undergoing shoulder replacement, patients with obesity had lower mortality than those with a healthy BMI, suggesting that BMI alone should not restrict access to surgery. Medscape Medical News
- An 18-week lifestyle medicine program improves 90-day postsurgery outcomes compared with standard of care. Medscape Medical News
- An estimated 1 million people in the US use wheelchairs full time for mobility. Medscape Medical News
- Adding menopause questions to NHS health checks could improve awareness, support early intervention, and help reduce long-term health risks for women. Medscape UK
